Functional Analyses of the Three Simian Hemorrhagic Fever Virus Nonstructural Protein 1 Papain-Like Proteases

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Functional analyses of the three simian hemorrhagic fever virus nonstructural protein 1 papain-like proteases.

UNLABELLED The N-terminal region of simian hemorrhagic fever virus (SHFV) nonstructural polyprotein 1a is predicted to encode three papain-like proteases (PLP1α, PLP1β, and PLP1γ). Catalytic residues and cleavage sites for each of the SHFV PLP1s were predicted by alignment of the SHFV PLP1 region sequences with each other as well as with those of other arteriviruses, and the predicted catalytic...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2014

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.01020-14